Systematic Reviews Synthesis
Full systematic reviews, meta-analyses, and rapid reviews in internal medicine. PRISMA- and Cochrane-aligned, reproducible, and delivered as a fixed-scope product.
If the next step for your program depends on knowing exactly what the evidence says - for a regulatory submission, a scientific platform, a grant, or a clinical decision - the review needs to be defensible. We deliver systematic literature reviews, meta-analyses, and rapid reviews that hold up. Documented search strategy. Dual-reviewer screening with conflict resolution. Data extraction tables. PRISMA flow diagram. Risk-of-bias assessment using RoB 2 or ROBINS-I. A synthesis report that can stand alone or become a manuscript. Three scope tiers so you can match the depth to the decision it has to support. Reach out with your research question and we'll recommend the right tier.
If the next step for your program depends on knowing exactly what the evidence says - for a regulatory submission, a scientific platform, a grant, or a clinical decision - the review needs to be defensible. We deliver systematic literature reviews, meta-analyses, and rapid reviews that hold up. Documented search strategy. Dual-reviewer screening with conflict resolution. Data extraction tables. PRISMA flow diagram. Risk-of-bias assessment using RoB 2 or ROBINS-I. A synthesis report that can stand alone or become a manuscript. Three scope tiers so you can match the depth to the decision it has to support. Reach out with your research question and we'll recommend the right tier.
Benefit
Defensible methodology. PRISMA and Cochrane standards applied end to end.
Reproducible. Search strategy, inclusion criteria, and extraction fields documented and reusable.
Dual-reviewer screening. Two reviewers, explicit conflict resolution.
Risk of bias assessed. RoB 2 or ROBINS-I applied per study design.
Scope that matches the decision. Rapid, standard SLR, or SLR with meta-analysis.
What's Included
A documented protocol - research question, inclusion / exclusion, and search strategy.
Database searches with records exported.
Dual-reviewer screening of titles, abstracts, and full texts.
Data extraction tables in a standardized format.
PRISMA flow diagram.
Risk-of-bias assessment with the appropriate tool.
Quantitative synthesis - meta-analysis with heterogeneity and sensitivity analyses - on the highest tier.
Synthesis report as a standalone deliverable or a manuscript-ready evidence summary.
Process
Research question call. Frame the question and choose the scope tier.
Protocol. We draft, you review, we sign off.
Search execution. Searches run in the agreed databases.
Screening. Dual-reviewer title/abstract and full-text screening.
Data extraction. Into the agreed tables.
Risk-of-bias assessment. RoB 2, ROBINS-I, or equivalent.
Synthesis. Narrative or quantitative per scope tier.
Report. PRISMA flow, tables, and final report delivered.
Unit of delivery: one review per research question. Pricing: fixed price per scope tier. Turnaround: 4 to 10 weeks depending on scope and evidence base volume.
Bring us your research question - we'll recommend the tier that fits.
Benefit
Defensible methodology. PRISMA and Cochrane standards applied end to end.
Reproducible. Search strategy, inclusion criteria, and extraction fields documented and reusable.
Dual-reviewer screening. Two reviewers, explicit conflict resolution.
Risk of bias assessed. RoB 2 or ROBINS-I applied per study design.
Scope that matches the decision. Rapid, standard SLR, or SLR with meta-analysis.
What's Included
A documented protocol - research question, inclusion / exclusion, and search strategy.
Database searches with records exported.
Dual-reviewer screening of titles, abstracts, and full texts.
Data extraction tables in a standardized format.
PRISMA flow diagram.
Risk-of-bias assessment with the appropriate tool.
Quantitative synthesis - meta-analysis with heterogeneity and sensitivity analyses - on the highest tier.
Synthesis report as a standalone deliverable or a manuscript-ready evidence summary.
Process
Research question call. Frame the question and choose the scope tier.
Protocol. We draft, you review, we sign off.
Search execution. Searches run in the agreed databases.
Screening. Dual-reviewer title/abstract and full-text screening.
Data extraction. Into the agreed tables.
Risk-of-bias assessment. RoB 2, ROBINS-I, or equivalent.
Synthesis. Narrative or quantitative per scope tier.
Report. PRISMA flow, tables, and final report delivered.
Unit of delivery: one review per research question. Pricing: fixed price per scope tier. Turnaround: 4 to 10 weeks depending on scope and evidence base volume.
Bring us your research question - we'll recommend the tier that fits.
Question in mind?
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Question in mind?